Mayes McEntire, DMD, MS

Endodontist in Columbia, SC

Columbia SC Endodontist Dr Mayes McEntire

Dr. Mayes McEntire grew up in Newberry, South Carolina, and graduated with honors from Presbyterian College. He completed Dental School at the Medical University of South Carolina and then attended The Ohio State University where he received his Specialty Certificate in Endodontics and his Masters of Science.

While at Ohio State, he completed extensive clinical research involving local anesthesia and is committed to providing pain free endodontic procedures for his patients.

Dr. McEntire returned to South Carolina in 2009 to join Palmetto Endodontics and has performed thousands of endodontic procedures.

Ready to Schedule Your Appointment with Dr. McEntire?
Call Forest Drive Phone Number 803-782-7722 to Schedule Your Appointment!


  • The Ohio State University: Certificate in Endodontics and Masters of Science, 2009
  • The Medical University of South Carolina: DMD, 2007
  • Presbyterian College: BS Biology, 2003

Professional History

  • Palmetto Endodontics, LLC, Columbia, SC: Endodontist (2009 – Present)

Professional Organizations/Affiliations


  • Anesthetic Efficacy of 4% Articaine with 1:100,000 Epinephrine versus 4% Articaine with 1:200,000 Epinephrine as a Primary Buccal Infiltration in the Mandibular First Molar Mayes McEntire DMD, MS, John Nusstein DMD, MS, Melissa Drum DMD, MS, Al Reader DMD, MS, Mike Beck DDS, MA. Journal of Endodontics Vol. 37 Issue 4, p.450-454.

Activities & Interests

Dr. McEntire and his family reside in Lexington. When he is not working, he enjoys spending time with his family, playing golf, following college athletics and boating.

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Palmetto Endodontics

5 out of 5 stars based on 59 Mayes McEntire reviews.

Patient Review

This was the best dental experience I have had so far. Dr. McEntire is very gentle and patient and the procedure was painless

- Danika m

5 out of 5 stars on

Patient Review

My root canal was painless and would definitely use Dr. McEntire again if needed. Very patient and made sure I was comfortable the whole time.

- Georgia C

5 out of 5 stars on

Patient Review

Nobody wants to get a Root Canal. I’ll tell you this I have had several over the years and this by far was the best experience I have ever had. I was in and out of the office in record time. The quality of work cannot be matched. The staff was AMAZING. They made sure I was extremely comfortable throughout the entire procedure. I kept waiting for the pain to hit. I’m still waiting. It was Virtually painless. I recommend Palmetto Endodontics to anyone looking for a PAIN FREE PROFESSIONAL Dental experience.

- Raleigh H

5 out of 5 stars on