Mayes McEntire, DMD, MS

Endodontist in Columbia, SC

Columbia SC Endodontist Dr Mayes McEntire

Dr. Mayes McEntire grew up in Newberry, South Carolina, and graduated with honors from Presbyterian College. He completed Dental School at the Medical University of South Carolina and then attended The Ohio State University where he received his Specialty Certificate in Endodontics and his Masters of Science.

While at Ohio State, he completed extensive clinical research involving local anesthesia and is committed to providing pain free endodontic procedures for his patients.

Dr. McEntire returned to South Carolina in 2009 to join Palmetto Endodontics and has performed thousands of endodontic procedures.

Ready to Schedule Your Appointment with Dr. McEntire?
Call Forest Drive Phone Number 803-782-7722 to Schedule Your Appointment!


  • The Ohio State University: Certificate in Endodontics and Masters of Science, 2009
  • The Medical University of South Carolina: DMD, 2007
  • Presbyterian College: BS Biology, 2003

Professional History

  • Palmetto Endodontics, LLC, Columbia, SC: Endodontist (2009 – Present)

Professional Organizations/Affiliations


  • Anesthetic Efficacy of 4% Articaine with 1:100,000 Epinephrine versus 4% Articaine with 1:200,000 Epinephrine as a Primary Buccal Infiltration in the Mandibular First Molar Mayes McEntire DMD, MS, John Nusstein DMD, MS, Melissa Drum DMD, MS, Al Reader DMD, MS, Mike Beck DDS, MA. Journal of Endodontics Vol. 37 Issue 4, p.450-454.

Activities & Interests

Dr. McEntire and his family reside in Lexington. When he is not working, he enjoys spending time with his family, playing golf, following college athletics and boating.

Palmetto Endodontics

5 out of 5 stars based on 57 Mayes McEntire reviews.

Patient Review

my overall experience with Dr.McEntire was definitely one of the best visit that I've ever experience at any dentist office from Ga to South Carolina. My mouth had severe nerve Faith, and reassurance, along with his awesome staff , I made it through. "Thank You Lord I Survived."

- Tia B

5 out of 5 stars on

Patient Review

I have had at least 3 prior root canals. Today was my first where I started falling asleep ! Painless, as most root canals are (unless abscess is there, then you have pain) In this case , the way the Dr and tech work together is what makes the technique go quicker and without making you nervous. Being asked how you are , often, means alot to me.

- Ruthie H

5 out of 5 stars on

Patient Review

The moment I walked into the office the staff was so friendly. I want to thank Dr McEntire for fitting me in on his lunch break to do my root canal. I had been in severe pain for days and the moment I went into the office he fit me in on his lunch break. Thank you so much!

- Crystal L

5 out of 5 stars on