Mayes McEntire, DMD, MS

Endodontist in Columbia, SC

Columbia SC Endodontist Dr Mayes McEntire

Dr. Mayes McEntire grew up in Newberry, South Carolina, and graduated with honors from Presbyterian College. He completed Dental School at the Medical University of South Carolina and then attended The Ohio State University where he received his Specialty Certificate in Endodontics and his Masters of Science.

While at Ohio State, he completed extensive clinical research involving local anesthesia and is committed to providing pain free endodontic procedures for his patients.

Dr. McEntire returned to South Carolina in 2009 to join Palmetto Endodontics and has performed thousands of endodontic procedures.

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Call Forest Drive Phone Number 803-782-7722 to Schedule Your Appointment!


  • The Ohio State University: Certificate in Endodontics and Masters of Science, 2009
  • The Medical University of South Carolina: DMD, 2007
  • Presbyterian College: BS Biology, 2003

Professional History

  • Palmetto Endodontics, LLC, Columbia, SC: Endodontist (2009 – Present)

Professional Organizations/Affiliations


  • Anesthetic Efficacy of 4% Articaine with 1:100,000 Epinephrine versus 4% Articaine with 1:200,000 Epinephrine as a Primary Buccal Infiltration in the Mandibular First Molar Mayes McEntire DMD, MS, John Nusstein DMD, MS, Melissa Drum DMD, MS, Al Reader DMD, MS, Mike Beck DDS, MA. Journal of Endodontics Vol. 37 Issue 4, p.450-454.

Activities & Interests

Dr. McEntire and his family reside in Lexington. When he is not working, he enjoys spending time with his family, playing golf, following college athletics and boating.

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Palmetto Endodontics

5 out of 5 stars based on 59 Mayes McEntire reviews.

Patient Review

I needed a good bit of work and these folks were great. Dr McEntire also helped me communicate better with my general dentist. It made a big difference for me. Thanks

- Chris W

5 out of 5 stars on

Patient Review

The overall experience at this dental office with the doctor and staff was extremely professional and kind. My discomfort was addressed quickly and efficiently. The Dr. even offered to make an appointment available during his lunch hour so that I could be seen to get me out of pain. And the office décor is incredible.


5 out of 5 stars on

Patient Review

I was terrified about having a root canal from the stories I was told by others. I can honestly say that they were all wrong! The procedure was painless, and my doctor (Mayes McEntire) did an awesome job in performing my root canal. He demonstrated so much compassion, and that took the fear completely away. I had the best experience. Many thanks to the staff and my wonderful doctor for taking good care of me. I will definitely recommend Palmetto Endodontics to everyone.

- Brenda D

5 out of 5 stars on